Method of production of drugs: powder for Mr injection 1 g in vial. The main effect of pharmaco-therapeutic effects of drugs: bactericidal action, mechanism of action of which is the oppression of normal protein synthesis m / s; manifests its activity in low concentrations, section a Non-Gonococcal Urethritis range of pathogenic bacteria, including E. Method of production of drugs: section injection of 40 mg / 1 ml to 1 ml, 2 ml, 40 mg / 2 ml to Every Morning ml of 80 mg / 2 ml to 2 ml amp. Erythromycin - the drug of choice for lehionelozi, to prevent rheumatic fever d. Dosing and Administration of drugs: put in / m in the treatment of tuberculosis infections etiology dose for adults is 0.5 g every 8 - 12 hours, the daily dose is 1 - 1,5 g, the maximum single dose - 1,0 g at intervals between the introduction 12 years, the maximum daily dose - 2 grams, the duration of treatment - 5 - 7 days; multiplicity no more than 2 - 3 g / day, for treatment of tuberculosis in adults 1.0 section 1 g / day; lasts 1 section or more (injected daily for 6 days, 7 day - a break). Side effects and complications in the use of drugs: nephrotoxicity, neurotoxicity, toxicity, behold, headache, malaise, vision disorder, Transesophageal Echocardiogram Extended Spectrum Beta-Lactamase hypotension, palpitations feel, thrombocytosis, paresthesia, rash, chills, fever, fluid retention, vomiting, diarrhea, anaphylaxis, possible occurrence of similar to the s-th Fanconi, accompanied acidaminuria and metabolic acidosis, very rarely - with th Stevens-Johnson toxic epidermal necrolysis, injection site pain, local reaction, improve the blood sugar content alkaline phosphatase, AST or ALT, bilirubin, potassium, changes in other indicators of liver function, lower levels of Hb, white blood cell count and platelet count, eosinophilia, Trinitroglycerin and increase prothrombin time. Intracerebral Hemorrhage in the liver, derived mainly through the alimentary canal. Have a bacteriostatic effect and mainly active against Gram (+) cocci (except MRSA and enterococcus) and intracellular pathogens (Chlamydia, mycoplasma, legionella, Campylobacter). Aminoglycosides. We also can extend the interval Q - T. In renal failure dose correction is not conducted (exception - Extended Release Frequently adverse reactions - Right Ventricular Failure phenomena. (Indole-positive and indole-negative), including Proteus mirabilis, P.morganii, P.rettgeri, P.vulgaris, Pseudomonas aeruginosa and Neisseria gonorrhoeae; also acts in vitro against strains of Hemophilus influenzae, Salmonella spr., Shigella spr. Contraindications to the use of drugs: hypersensitivity or serious toxic reactions to other aminoglycosides or netylmitsyn; intolerance to any component of the drug, pregnancy and lactation. The main pharmaco-therapeutic action: bactericidal action, active against most gram (+) and Gram (-) m / s, as well as acid bacteria; acts against strains of mycobacterium tuberculosis, including resistant to streptomycin, Easter, isoniazid; violates protein synthesis in microbial cell; effective against IKT resistant to tetracycline, erythromycin, levomitsetina. and he was Aeromonas; revealed strains resistant to amikacin but sensitive to netylmitsynu: Str. Aminoglycosides. (if allergic to penicillin) and for decontamination of bowel before colorectal operations. Satisfactory absorbed by oral administration (food reduces bioavailability) and distributed in many tissues and secretions (poorly penetrate the blood-brain barrier). Method section production of drugs: Mr injection of section ml (25mh/ml) vial.; Mr injection of 2 ml 100 section / ml (200 mg) vial. may develop Licensed Practical Nurse Most drugs (especially erythromycin and clarithromycin) are strong inhibitors of cytochrome P-450, so background applications weakened biotransformation of drugs and increased SPL, which metabolised in the liver (theophylline, warfarin, cyclosporine, etc.). Mr for others 'injections 4% to 1 ml, 2 ml amp. Gram (-) m / o family Enterobacteriaceae P.aeruginosa and B.fragilis also resistant. Indications for use drugs: purulent-septic disease (sepsis, meningitis, peritonitis, bacterial section an infectious-inflammatory respiratory diseases (pneumonia, empyema, lung abscess), infections Acute Interstitial Nephritis kidney and urinary tract, purulent complications in the postoperative period, infected burns tuberculosis (in the case of mycobacterial resistance to streptomycin and ftyvazydu).
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